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January 03, 2012

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New QMCF Technology application: generation of Cell based translocation assays has been launched

In December 2011 Icosagen Cell Factory completed a two-years applied research project to use QMCF Technology for screening of target proteins in cell based assays for signal pathway studies and high-content screening applications.



QMCF Technology is a time saving tool for screening target proteins in cell based assays for signal pathway studies and high-content screening applications.

Stable maintenance, segregation and replication of QMCF expression plasmids in QMCF cells allow generation of stable expression system within 2-3 weeks after transfection. Generation of expression cell banks enables to obtain ready-to-monitor cell cultures.

QMCF Technology based assay system consists of:

  • CHO and U2OS based modified adherent QMCF cell lines and
  • compatible QMCF expression plasmids that are stably maintained by QMCF cell lines
  • target visualization by immunofluorescence and fluorescent protein based universal detection systems


The project has been granted by Enterprise Estonia for 1,0 million euros.

Read more about QMCF based cell based assays